Not currently in practice. Jerrin Mathew is a licensed Registered Nurse (RN, BSN) enrolled in a graduate psychiatric-mental health nurse practitioner program. He is not a licensed Advanced Practice Registered Nurse, is not accepting patients, and does not provide psychiatric evaluation, treatment, diagnosis, or prescribing services. This site is educational only.
JMJerrin Mathew
Writing/Mental health and substance use

Stimulant misuse in high-performing professionals

A legitimate prescription becomes a dependency when the dose keeps climbing and stopping feels impossible.

For medical and professional workers in Illinois: This article reflects clinical evidence and direct experience. If you're in the Chicago area or Illinois, contact me to discuss your concerns.

A legitimate prescription for ADHD begins as a tool. For some people it becomes something else gradually, and the person using it often notices late.

The progression is remarkably consistent in professionals. The dose prescribed works, and then it stops working quite as well. The next appointment, the dose goes up. This is ordinary titration and completely appropriate. But sometimes the sense of needing more continues past where the prescriber has approved, and the person finds themselves taking more than prescribed, or taking it in different ways, or counting the pills before the month is done.

How it differs from therapeutic use

Therapeutic stimulant use means the dose is stable, the person uses it as prescribed, they experience benefit with manageable side effects, and they could stop it if they needed to.

Misuse involves escalating dose, using it differently than prescribed, spending substantial time obtaining it, experiencing cravings, or continuing despite negative consequences. The dose that was perfect stops feeling like enough.

This is not a character issue or a sign of moral weakness. It is what happens when someone with ADHD and high occupational stress tries to manage both with the available tool. The stimulant genuinely helps performance, so needing more feels like needing a higher dose for a legitimate medical condition rather than like misuse.

The professional vulnerability

Several things collude to make professionals particularly vulnerable. Stimulant use is normalized in demanding fields. A person can justify the dose escalation by pointing to increased work. And the symptom — needing more to maintain performance — can look identical whether it is tolerance or whether the underlying ADHD has worsened under stress.

Someone can go from prescribed 20mg to taking 60mg without ever explicitly deciding to become someone who misuses stimulants. Each increase felt like reasonable adjustment.

What happens with withdrawal

Unlike alcohol or benzodiazepines, stimulant withdrawal is not medically dangerous. But it is powerfully unpleasant. Stopping after prolonged heavy use produces severe fatigue, depression, anhedonia — nothing feels good or worthwhile — and a sense of being unable to focus or function at all.

This is a real phenomenon and not psychological weakness. It is what the brain does after sustained dopamine elevation when the dopamine supply suddenly stops.

It is also why medical management matters. Tapering slowly rather than stopping abruptly, addressing the depression that often appears, and sometimes transitioning to appropriate therapeutic dosing of a single agent rather than attempting abstinence, all make stopping substantially more feasible.

The distinction from ADHD treatment

Someone can have ADHD, take a stimulant appropriately, and then develop stimulant misuse on top of that. The two are not mutually exclusive.

Treating this usually means separating them: stabilizing the ADHD on an appropriate therapeutic dose with one agent while addressing the misuse pattern separately, often with professional support and sometimes with a different medication.

Why it warrants attention

Stimulant misuse in professionals tends to go untreated longer than it should because everyone involved has reasonable explanations for the dose. The person is working extremely hard. Their performance is visible and impressive. The dose keeps going up and nobody is yet calling it misuse.

By the time it is obvious, the person is often deeply invested in the arrangement and genuinely uncertain how they would function without it.

Early recognition — noticing that the dose has escalated, that you think about the next dose before you need it, that you are using it in ways your prescriber didn't describe — makes the path back simpler.

Medical disclaimerThis article is educational and is not medical advice. Stimulant misuse and dependence require professional evaluation and treatment. Abrupt discontinuation can produce severe fatigue and depression and should be managed medically. If you are concerned about your stimulant use, speak with a healthcare provider.
References
  1. National Institute on Drug Abuse. Prescription stimulants. https://nida.nih.gov/publications/drugfacts/prescription-stimulants
  2. Substance Abuse and Mental Health Services Administration. Substance use disorder treatment. https://www.samhsa.gov/substance-use/treatment
  3. Substance Abuse and Mental Health Services Administration. Co-occurring disorders. https://www.samhsa.gov/substance-use/treatment/co-occurring-disorders
  4. Centers for Disease Control and Prevention. Treatment of ADHD. https://www.cdc.gov/adhd/treatment/

Published August 2026 · Reviewed for accuracy against the sources listed above.

About the author

Jerrin Mathew, RN, BSN

Registered nurse with a clinical background spanning emergency medical services, long-term acute care, cardiac telemetry, and neurocritical care at a Level I trauma center. Currently completing graduate education in psychiatric-mental health nursing, with an expected graduation in 2027.

Writing here focuses on the intersection of psychiatric illness and demanding professional life — what gets missed, what gets mislabelled, and what is worth taking to a clinician.

More about my background →
Jerrin Mathew RN, BSN, PMHNP Student

Available in Chicago and Illinois. If you're in the Chicago area, Illinois, or surrounding Midwest and want to discuss your concerns, contact me for a free consultation.